Weight-Loss Drugs May Slow Aging, But Side Effects Raise Questions

GLP-1 drugs, originally for diabetes, are now widely used for weight loss. Recent research suggests they might also slow aging: people taking them had a biological age 2-3 years younger than those on placebo. This adds to other potential benefits like treating substance abuse or neurodegenerative diseases. With 11% of Americans using them, these drugs are incredibly popular and effective for weight loss.

However, side effects are a growing concern. Common ones include nausea, vomiting, and constipation. More serious risks include pancreatitis, gallstones, and possibly vision loss—dozens are suing manufacturers. Hair loss and nail disorders have also been reported, though rare. The full picture is still unclear, and research is ongoing.

Children are a particular worry. Prescriptions for kids aged 8-11 with obesity surged 310-fold between 2019 and 2026. The WHO now advises against pharmacological treatment for children under 10 due to lack of evidence on safety and long-term effects. As more people take these drugs, understanding their full impact is crucial.