Research & Papers

Mycelium: Active shared context graphs turn teams into networked intelligence

New system connects human researchers and AI agents via shared context graphs, tested in multi-omics campaign.

Deep Dive

Most AI-for-science systems focus on improving a single reasoning process through better models or larger context windows. But real scientific breakthroughs emerge from teams with diverse priors, experimental backgrounds, and tacit knowledge. The challenge is not just scaling models but cultivating networked intelligence—scaling connections between humans and AI so that insights flow to the right person, agent, or instrument. To address this, Sutanay Choudhury and 17 co-authors from Pacific Northwest National Laboratory (PNNL) and other institutions introduce Mycelium, an active shared workspace that functions as a multi-user co-scientist. As human users and AI agents work, the system captures observations and hypotheses, tracks their relationships to the team's evolving model, and routes them automatically to the human or agent who can act on them.

Mycelium was tested in its first empirical evaluation: a biological multi-omics campaign. The system demonstrated that routed shared context could transform a local analytical finding into a cross-expert mechanistic constraint, ultimately shaping an experimental design. The paper also provides a formal computational account of networked intelligence as sparse conditional computation over distributed scientific contexts. This theory distinguishes when a scaled standalone agent can match the network's performance versus when independent expertise and non-mergeable contexts make the network irreducible. By enabling dynamic, context-aware collaboration between multiple humans and multiple AI agents, Mycelium represents a paradigm shift from single-reasoner AI assistants to true team-wide co-intelligence.

Key Points
  • Mycelium is a multi-user co-scientist that automatically routes observations and hypotheses to the right team member based on evolving shared context.
  • In a multi-omics campaign, routed context turned a local analytical finding into a cross-expert mechanistic constraint and experimental design.
  • The paper offers a computational account of networked intelligence as sparse conditional computation, identifying conditions where stand-alone agents cannot match the network.

Why It Matters

Mycelium enables AI to amplify not just individual scientists but entire research teams, accelerating complex multi-domain discoveries.

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