Research & Papers

CL API: Real-Time Closed-Loop Interactions with Biological Neural Networks

Scientists just created a Python API to program biological neural networks in real-time.

Deep Dive

Cortical Labs has unveiled the CL API, a new tool allowing researchers to program and interact with living biological neural networks (BNNs) in real-time with sub-millisecond precision. The declarative Python interface lets non-experts design complex stimulation and closed-loop experiments without managing low-level hardware, overcoming a major trade-off between control and accessibility. This provides a reproducible foundation for both neuroscience research and emerging neurocomputing applications where brains act as a novel computing substrate.

Why It Matters

This bridges neuroscience and computer science, making brain-cell-based computing accessible and reproducible for the first time.